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Table 3 Summary of validation results by program and combination of programs

From: A simple consensus approach improves somatic mutation prediction accuracy

Call set

Specificity

Sensitivity

MuTect

82.8%a

94.8%b

JointSNVMix2

78.6%a

85.2%b

SomaticSniper

74.5%a

95.6%b

Consensus of 3 programs

98.9%c

78.2%d

Consensus of 2+ programs

86.1% c

97.4% d

All variants

38.6%c

100%d

  1. Abbreviations: TP, true positive.
  2. aNumber of TPs predicted by program/all predictions by program for which validation was attempted.
  3. bNumber of TPs predicted by program/all TPs.
  4. cNumber of TPs predicted in the group/all predictions by program for which validation was attempted.
  5. dNumber of TPs predicted in the group/all TPs.