From: A simple consensus approach improves somatic mutation prediction accuracy
 | Validation ratea |  |  | TP dropout rated |
---|---|---|---|---|
 | Partial consensusb | No consensusc | Overall |  |
Base validation ratee | 44/78 (56%) | 6/105 (6%) | 50/183 (27%) | Â |
Percentage of mate-rescued reads <7%f | 44/64 (64%) | 6/69 (9%) | 50/133 (38%) | 0% |
RD >10 (tumor and germline)g | 40/68 (59%) | 5/72 (7%) | 45/140 (32%) | 10% |
Germline non-reference allele frequency ≤0.02h | 42/65 (65%) | 6/75 (8%) | 48/140 (34%) | 4% |
GATK prediction for SNV in tumori | 43/66 (66%) | 5/47 (11%) | 48/113 (42%) | 4% |
GATK + mate-rescued | 43/56 (77%) | 5/31 (16%) | 48/87 (55%) | 4% |
GATK + mate-rescued + RD >10 | 39/46 (85%) | 4/19 (21%) | 43/65 (66%) | 14% |