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Table 3 Number of validated true/false sSNVs detected using the five tools in the lung cancer samples

From: Detecting somatic point mutations in cancer genome sequencing data: a comparison of mutation callers

Tool Lung tumors (n = 18)   Lung cancer cell lines (n = 7)   Totala   
TP FP TP FP TP FP
# High quality # Low quality # High quality # Low quality # High quality # Low quality
JointSNVMix 30 17 6 49 0 11 79 17 17
MuTect 30 19 11 47 0 7 77 19 18
SomaticSniper 33 17 10 47 0 9 80 17 19
Strelka 27 17 8 51 0 10 78 17 18
Varscan 2 35 8 5 51 0 13 86 8 18
  1. aTotal is the sum of #sSNVs found in lung tumors and lung cancer cell lines.
  2. FP: false-positive sSNVs; TP: true-positive sSNVs.