A robust prognostic signature for hormone-positive node-negative breast cancer

Table 1 Studies included in analysis

Study	GSE	Total samples	ER+/LN-/ untreated^a/outcome	Duplicates removed	ER+/HER2-array	10-year relapse	10-year no relapse
Desmedt, 2007 [3]	GSE7390	198	135	135	116	42	60
Ivshina, 2006 [4]	GSE4922	290	133	2	2	0	2
Loi, 2007 [5]	GSE6532	327	170	43	40	10	5
Miller, 2005 [6]	GSE3494	251	132	115	100	30	52
Schmidt, 2008 [7]	GSE11121	200	200^b	200	155	25	46
Sotiriou, 2006 [8]	GSE2990	189	113	48	45	12	15
Symmans, 2010 [9]	GSE17705	298	175	110	102	12	41
Wang, 2005 [10]	GSE2034	286	209	209	173	67	29
Zhang, 2009 [11]	GSE12093	136	136	136	125	15	24
Nine studies		2,175	1403	998	858	213	274

^aUntreated includes some patients with adjuvant endocrine therapy alone or radiation.
^bER status not available, filtered later based on array expression data.

ISSN: 1756-994X