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Table 4 Comparison of validation results in independent test data for full-gene-set, 17-gene, and eight-gene RFRS models

From: A robust prognostic signature for hormone-positive node-negative breast cancer

   Relapse-free survival   
RFRS performance   Low risk   Intermediate risk   High risk   
Model AUC RR n (%) RR n (%) RR n (%) KM ( P )
Full-gene-set 0.730 6.9 78 (30.7) 15.8 133 (52.4) 26.8 43 (16.9) 6.54E-06
17-gene 0.715 7.8 97 (38.2) 15.3 103 (40.5) 26.8 54 (21.3) 9.57E-06
Eight-gene 0.690 9.7 101 (39.8) 13.9 105 (41.3) 28.3 48 (18.9) 2.84E-05
  1. KM (P), p-value for Kaplan-Meier logrank test (with test for linear trend) from survival analysis; RR, relapse rate.