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Table 1 Proteins unchanged at P1 but increased >50% or 20 to 50% at P5 in the rostral band of LAL muscle from SMA mice compared with littermate controls

From: Label-free proteomics identifies Calreticulin and GRP75/Mortalin as peripherally accessible protein biomarkers for spinal muscular atrophy

Gene name Protein name Accession number Peptides at P5 Ratio KO/control P1 Ratio KO/control at P5 Score at P5 Anova ( P-value) at P5
G6pI Glucose-6-phosphate isomerase G6PI_MOUSE 6 1.03 1.98 245.68 6.92E-06
Grp75 Stress-70 protein GRP75_MOUSE 3 1.02 1.82 170.83 5.59E-04
Tbb5 Tubulin beta-5 chain TBB5_MOUSE 2 1.02 1.80 639.05 3.69E-05
Plec1 Plectin-1 PLEC1_MOUSE 21 1.18 1.63 879.72 4.67E-06
Thil Acetyl-CoA acetyltransferase THIL_MOUSE 7 1.09 1.59 448.39 2.95E-04
Calr Calreticulin CALR_MOUSE 3 1.12 1.51 83.76 2.08E-03
Aatm Aspartate aminotransferase AATM_MOUSE 7 1.17 1.50 443.54 1.50E-04
Thim 3-Ketoacyl-CoA thiolase THIM_MOUSE 12 1.02 1.41 473.14 1.16E-03
Anxa2 Annexin A2 ANXA2_MOUSE 10 1.04 1.33 729.11 1.28E-03
Pura1 Adenylosuccinate synthetase isozyme 1 PURA1_MOUSE 5 1.09 1.30 247.24 1.19E-03
S10ab Protein S100-A11 S10AB_MOUSE 2 1.01 1.25 166.21 2.78E-02
Hbb2 Hemoglobin subunit beta-2 HBB2_MOUSE 6 1.01 1.23 702.27 1.51E-03
Lmna Lamin-A/C LMNA_MOUSE 7 1.16 1.21 567.31 2.19E-04
Vime Vimentin VIME_MOUSE 12 1.17 1.21 776.2 3.50E-04
  1. KO, knockout.