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Table 2 Proteins unchanged at P1 but decreased >50% or 20 to 50% at P5 in the rostral band of LAL muscle from SMA mice compared with littermate controls

From: Label-free proteomics identifies Calreticulin and GRP75/Mortalin as peripherally accessible protein biomarkers for spinal muscular atrophy

Gene name Protein name Accession number Peptides at P5 Ratio KO/control at P1 Ratio KO/control at P5 Score at P5 Anova ( P-value) at P5
Rrbp1 Ribosome-binding protein 1 RRBP1_MOUSE 3 0.89 0.15 60.23 1.97E-05
Tpm1 Tropomyosin alpha-1 chain TPM1_MOUSE 6 0.92 0.25 652.67 6.87E-06
Actn2 Alpha-actinin-2 ACTN2_MOUSE 15 0.89 0.61 1413.57 1.82E-04
Tcpb T-complex protein 1 subunit beta TCPB_MOUSE 3 0.89 0.66 162.09 2.07E-03
Postn Periostin POSTN_MOUSE 3 0.99 0.70 142.66 7.55E-04
Hs90a Heat shock protein HSP 90-alpha HS90A_MOUSE 3 0.99 0.70 326.05 7.71E-04
Hs90b Heat shock protein HSP 90-beta HS90B_MOUSE 8 0.90 0.70 600.51 6.45E-05
Rtn4 Reticulon-4 RTN4_MOUSE 5 0.86 0.79 123.82 1.69E-02
Nb5r3 NADH-cytochrome b5 reductase 3 NB5R3_MOUSE 3 0.95 0.79 65.43 3.90E-05
  1. KO, knockout.