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Table 2 The frequencies of estimated haplotypes† for eight CHD-associated SNPs in seven different geographic regions

From: Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease

rs10116277

rs1537370

rs10738607

rs4977574

rs944797

rs2383207

rs1537375

rs1333049

Africa N = 102

Middle East N = 160

Europe N = 156

C.S. Asia N = 200

E. Asia N = 229

Oceania N = 28

America N = 63

G

C

T

A

A

A

T

G

NF

0.209

0.384

0.327

0.328

0.554

0.449

T

T

C

G*

G*

G*

C*

C

0.115

0.516

0.536

0.478

0.470

0.161

0.302

T

T

C

G*

G*

G*

C*

G

NF

0.100

0.031

0.029

NF

0.143

NF

G

C

C

G*

G*

G*

C*

C

NF

0.021

0.017

NF

0.019

NF

0.032

T

T

C

A

G

G

C

G

0.021

0.019

NF

NF

NF

NF

NF

T

T

T

A

A

G

C

G

0.345

0.041

NF

NF

NF

0.054

NF

T

C

T

A

A

G

C

G

0.246

0.013

NF

NF

NF

NF

0.016

T

T

C

A

A

G

C

G

NF

NF

NF

0,035

0.092

0.054

NF

T

T

T

A

G

G

T

G

0.129

0.031

NF

0,027

NF

NF

NF

G

C

T

A

G

G

C

C

NF

NF

NF

NF

NF

NF

0.147

G

C

T

A

A

G

C

G

0.027

NF

NF

NF

NF

0.036

NF

T

T

T

A

A

A

T

G

NF

0.019

NF

0,015

0.039

NF

0.012

G

C

T

A

A

A

T

C

NF

NF

NF

0,013

NF

NF

0.016

  1. The risk alleles in Europeans are in bold-face and italicized, and the core risk haplotype is marked with an asterisk. †Population-specific haplotypes <5% frequent were omitted. NF, haplotype not found in given geographic region.