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Figure 2 | Genome Medicine

Figure 2

From: Informed decision-making among students analyzing their personal genomes on a whole genome sequencing course: a longitudinal cohort study

Figure 2

Trends relating to decisional conflict overall scale and five subscales about using one’s personal genome in an advanced genome sequencing course. These were observed as part of a two-part genomics course taken by 19 students at the Icahn School of Medicine at Mount Sinai in 2012. All P values were calculated using paired samples t-tests. Lower scores indicate lower levels of decisional conflict. Scores are means with standard error bars displayed. (A) Decisional conflict about whether or not to get one’s own genome sequenced decreased over time between T1 and T2 (P < 0.001) and T1 and T3 (P < 0.001). The difference was not significant between T2 and T3 (P = 0.10). (B) Scores on the informed subscale decreased between T1 and T2 (P = 0.002) and between T1 and T3 (P < 0.001) indicating students felt more informed at T2 and T3 than they did at T1. (C) Scores on the effective decision-making subscale decreased between T1 and T2 (P = 0.001) and between T1 and T3 (P = 0.001), indicating students felt more satisfied with their decisions at T2 and T3 than they did at T1. (D) Scores on the support subscale decreased between T1 and T2 (P = 0.003) and between T1 and T3 (P = 0.003), indicating students felt more supported at T2 and T3 than they did at T1. (E) Scores on the values clarity subscale decreased between T1 and T2 (P = 0.012) and between T1 and T3 (P = 0.005), indicating students felt greater clarity about their values at T2 and T3 than they did at T1. (F) Scores on the uncertainty subscale decreased between T1 and T3 (P = 0.006), indicating students felt less uncertainty about their decisions at T3 than they did at T1.

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