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Table 2 Copy number variants associated with schizophrenia, their penetrance for schizophrenia, and associations with other psychiatric disorders and intellectual disability

From: Genomic insights into the overlap between psychiatric disorders: implications for research and clinical practice

Locus Copy number change Penetrance Associations References
1q21.1 Deletion/duplication 5.2/2.9 ID, ASD, ADHD [57, 58, 7175]
2p16.3 (NRXN1) Deletion 6.4 ID, ASD [57, 58, 74, 7681]
3q29 Deletion 18.0 ID, ASD [7375, 82]
7q11.2 Duplication 6.0 ID, ASD, ADHD, anxiety disorders [73, 74, 8386]
15q11.2 Deletion 2.0 ID, ASD, ADHD, OCD [7274, 81, 8789]
15q11-13 Duplication 4.2 ID, ASD [73, 74, 9092]
15q13.3 Deletion 4.7 ID, ASD, ADHD [57, 7275, 9396]
16p11.2 Deletion/duplication 2.6/8.0 ID, ASD, ADHD, mood disorders, anxiety disorders [62, 73, 74, 91, 97102]
16p13.11 Duplication 2.2 ID, ASD, ADHD [61, 73, 74, 81, 103, 104]
17q12 Deletion 4.0 ID, ASD [73, 74, 105]
22q11.2 Deletion 12 ID, ASD, ADHD, mood disorders, anxiety disorders [57, 73, 74, 106109]
  1. ASD, autism spectrum disorder; ADHD, attention-deficit/hyperactivity disorder; ID, intellectual disability; OCD, obsessive-compulsive disorder.