Figure 2From: Predicting targeted drug combinations based on Pareto optimal patterns of coexpression network connectivityDifferential coexpression among 1,044 genes differentially expressed by letrozole treatment in ER+ breast tumor samples. Coexpression is calculated as the first-order Spearman’s correlation coefficient for each pairwise combination of genes. Approximately 80% of coexpression relationships are found in only one of two treatment conditions and more coexpression relationships are formed among this gene set in the presence of letrozole. PostTx, post-treatment; PreTx, pre-treatment.Back to article page