Figure 1
From: Copy number variants are a common cause of non-syndromic hearing loss
A biallelic gene-pseudogene conversion of STRC is the causative mutation in patient 45. (a) Ratio plots showing apparent homozygous deletion of first 11 exons of STRC and duplication of first 11 exons of ψSTRC. (b) Hypothesized mechanism of gene-pseudo-gene conversion (non-allelic gene conversion in trans) and depiction of the biallelic change in the patient.