Molecularly and clinically related drugs and diseases are enriched in phenotypically similar drug-disease pairs

Table 1 Overview of different sets of diseases, drugs, and drug-disease pairs

	Diseases	Drugs	Drug-disease pairs
Disease/drug-feature pairs	55,031	155,973	-
With phenotypic features	4,869	1,667	8,116,623
With molecular information linked to human PPI	642	939	602,838
Drug-ADR-disease pairs/with PPI	1,294/76	736/619	34,467/1,442
Indications/with PPI	532/57	786/212	2,637/311
Contraindications/with PPI	229/23	948/58	2,230/61
Clinical trials/with PPI	813/68	1,022/197	7,744/381
In phenotypic similarity network	2,565	957	7,368
In network, with MeSH disease level 1	1,648	-	-
In network, with ATC information	-	805	-
In network, with MeSH disease level 2/drug MoA	939	379	1,352