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Table 1 Overview of different sets of diseases, drugs, and drug-disease pairs

From: Molecularly and clinically related drugs and diseases are enriched in phenotypically similar drug-disease pairs

  Diseases Drugs Drug-disease pairs
Disease/drug-feature pairs 55,031 155,973 -
With phenotypic features 4,869 1,667 8,116,623
With molecular information linked to human PPI 642 939 602,838
Drug-ADR-disease pairs/with PPI 1,294/76 736/619 34,467/1,442
Indications/with PPI 532/57 786/212 2,637/311
Contraindications/with PPI 229/23 948/58 2,230/61
Clinical trials/with PPI 813/68 1,022/197 7,744/381
In phenotypic similarity network 2,565 957 7,368
In network, with MeSH disease level 1 1,648 - -
In network, with ATC information - 805 -
In network, with MeSH disease level 2/drug MoA 939 379 1,352
  1. ADR, adverse drug reaction MoA, mechanisms of action.