Figure 2

Heritable and environmental factors contributing to disease. For each complex disease we show the fraction of the phenotypic variance explained by heritable factors, shared environmental factors, and non-shared environmental factors. The estimates were obtained from published studies of stomach, colorectum, pancreas, lung, breast, cervical, uterine, ovary, prostate, bladder and leukemia cancers [[29]]; strict autism [[27]]; psoriasis [[56]]; myocardial infarction [[57]]; gestational diabetes, type 1 diabetes, and type 2 diabetes [[25]].