Skip to main content


Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Figure 1 | Genome Medicine

Figure 1

From: VISPA: a computational pipeline for the identification and analysis of genomic vector integration sites

Figure 1

IS analysis procedure for the Roche 454 sequencing platform. (A) DNA fragments containing the vector-cellular genome junctions are retrieved and amplified from vector marked genomic DNA by LAM-PCR. (B) LAM-PCR products are processed by the NGS platform, yielding sequencing reads that have to be processed in silico. (C) Bioinformatics pipeline, from FASTA extraction to IS identification and annotation.

Back to article page