Figure 1
From: Whole-genome haplotyping approaches and genomic medicine
Overview of the three methods for phasing whole-genome sequence data. Phasing is achieved by (1) molecular methods, (2) genetic analysis, or (3) population inference. Molecular methods focus on individual samples and involve either (a) processing genomic DNA prior to sequencing or (b) leveraging the single-molecule characteristic of each physical read. Genetic analysis and population inference process sequenced genomes from pedigrees and population cohorts, respectively.