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Table 3 Univariate response analysis of metagenes stratified by proliferation tertile

From: Dual roles for immune metagenes in breast cancer prognosis and therapy prediction

Variable a

Odds ratio

P -value

(95% CI)

P L n = 222 (pr = 20, nr = 202)

  

 B/P

1.96 (1.30-2.93)

0.001

 T/NK

1.70 (1.04-2.77)

0.03

 M/D

1.64 (1.00-2.71)

0.51

P I n = 230 (pr = 48, nr = 182)

  

 B/P

1.39 (1.06-1.83)

0.02

 T/NK

2.17 (1.30-3.61)

0.003

 M/D

1.95 (1.30-2.93)

0.001

P H n = 228 (pr = 82, nr = 146)

  

 B/P

1.50 (1.15-1.96)

0.003

 T/NK

1.96 (1.24-3.07)

0.004

 M/D

1.96 (1.37-2.82)

0.0002

  1. B/P = B cells/plasma B cells; CI = confidence interval; M/D = monocyte/dendritic cell population; PH = high proliferation tertile; PI = intermediate proliferation tertile; PL = low proliferation tertile; T/NK = T cell/natural killer cell-specific population.
  2. aFor each tertile, 'n' is the number of cases in specified proliferation tertile, 'pr' is the number of responders, and 'nr' is the number of nonresponders.