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Table 4 Univariate response analysis of metagenes stratified by subtype

From: Dual roles for immune metagenes in breast cancer prognosis and therapy prediction

Variable a

Odds ratio

P -value

(95% CI)

Basal-like n = 205 (pr = 72, nr = 133)

 B/P

1.26 (0.95-1.68)

0.12

 T/NK

1.53 (0.93-2.51)

0.09

 M/D

1.66 (1.15-2.39)

0.007

Claudin-low n = 47 (pr = 17, nr = 30)

 B/P

1.92 (1.10-3.34)

0.02

 T/NK

2.08 (0.80-5.47)

0.14

 M/D

1.11 (0.43-2.86)

0.82

HER2-E n = 72 (pr = 26, nr = 46)

 B/P

1.31 (0.84-2.04)

0.23

 T/NK

0.83 ( 0.36-1.92)

0.67

 M/D

1.19 (0.54-2.59)

0.67

LumB n = 133 (pr = 23, nr = 110)

 B/P

1.33 (0.93-1.89)

0.11

 T/NK

1.44 ( 0.86-2.42)

0.16

 M/D

1.71(1.01-2.91)

0.05

LumA n = 207 (pr = 7, nr = 200)

 B/P

1.52 (0.82-2.83)

0.19

 T/NK

1.16 (0.52-2.60)

0.72

 M/D

0.93 (0.43-2.02)

0.85

  1. B/P = B cells/plasma B cells; CI = confidence interval; HER2-E, HER2-enriched; LumA = Luminal A; LumB = Luminal B; M/D = monocyte/dendritic cell population; T/NK = T cell/natural killer cell-specific population.
  2. aFor each subtype, 'n' is the number of cases, 'pr' is the number of responders, and 'nr' is the number of nonresponders.