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Table 1 Partial AUC performance and random permutation P value for three metrics using 152 filtered compound profiles

From: Systematic evaluation of connectivity map for disease indications

Method FPR = 0.01 (Specificity = 0.99) FPR = 0.1 (Specificity = 0.9)
Fold enrichment OneAUC0.01 Fold enrichment OneAUC0.1 AvgAUC0.1
KS 0.7 3.17e-5 (P = 0.94) 0.9 0.005 (P = 0.81) 0.003 (P = 0.90)
XSum 3.8 2.17e-4 ( P= 0.0035) 1.4 0.0086 ( P= 0.014) 0.011 ( P= 0.035)
XCos 2.3 1.82e-4 (P = 0.056) 1.2 0.006 (P = 0.16) 0.006 (P = 0.37)
  1. AvgAUC0.01 is not calculated because of limited sample size. Fold enrichment is calculated as the ratio between true positive rate and false positive rate.