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Figure 4 | Genome Medicine

Figure 4

From: Transcriptional fingerprints of antigen-presenting cell subsets in the human vaginal mucosa and skin reflect tissue-specific immune microenvironments

Figure 4

Transcriptional analysis of vaginal antigen-presenting cell subsets. (a) Hierarchical clustering (Pearson correlation) of the 1,559 transcripts differentially expressed (one-way ANOVA, P < 0.05, Benjamini-Hochberg correction) between the four vaginal APC populations. (b) Heatmap representing the results of Tukey’s test conducted after ANOVA. (c) Venn diagram of the 653 and 370 transcripts differentially expressed between vCD14- DCs and vMøs and between vLCs and vMøs. (d) Hierarchical clustering (Pearson correlation) of the 653 transcripts differentially expressed between vCD14- DCs and vMøs. (e) IPA network analysis for the 157 transcripts over-expressed in vCD14- DCs compared with vMøs. (f) IPA network analysis for the 496 transcripts over-expressed in vMøs compared with vCD14- DCs. (g) Bar chart representing the IPA canonical pathway enrichment in vCD14- DCs and vMøs. (h) Bar charts representing the batch-corrected expression values for selected transcripts over-expressed in vCD14- DCs (top row) or vMøs (bottom row).

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Genome Medicine

ISSN: 1756-994X

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