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Figure 1 | Genome Medicine

Figure 1

From: A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma

Figure 1

mRNA abundance patterns of 36-gene signature. Three genes (RFX8, RPSAP58 and GTF2IRD2B) were removed as over 50% of the validation cohort samples did not have corresponding expression profiles available given the annotation libraries used at the time of this study, and were therefore deemed unsuitable for clustering. The annotations on the right represent HGNC gene symbols along with asterisks indicating the significance of the mRNA-based differential expression between the predicted risk groups (***P adjusted < 0.001, **P adjusted < 0.01 and *P adjusted < 0.05). The covariates along the horizontal axis show a patient’s predicted risk group (black is low risk and red is high risk) and underlying dataset (red = Badea, green = Biankin, blue = Collisson, cyan = Donahue, magenta = Grutzmann, yellow = Pei, grey = Stratford and white = Winter). These results show two clusters of differential gene expression between the patient groups that demonstrate significantly different overall survival. HGNC, HUGO Gene Nomenclature Committee.

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