Plasmodium falciparumgene expression measured directly from tissue during human infection

Table 1 Summary of shared malaria genes overexpressed in three in vivo patient samples ^a

Category	Number	Description ^b	Gene names
Gametocyte/Mosquito	10	Maximal expression during gametocyte or mosquito stages	PFA0425c, PFC0581w, PFC0755c, MAL7P1.64, MAL7P1.109, PF10_0169, PF10_0204, PF11_0163, PF13_0350, PF14_0031
Trophozoite/Schizont	10	Maximal in vitro expression during late trophozoite or schizont stage	PFA0210c, PFI0810c, PFI1445w, PF10_0268, PF10_0330, PF11_0048, PF11_0156, PF11_0183, PFL1565c, PF14_0366
In vivo expressed	7	Genes with less than 100 RPKM for any stage in vitro	PFC0005w, PFI1600w, PFI1830c, PF11_0203, PFL1010c, PFL1195w, PF14_0363
Ribosomal	6	Ribosomal or putative ribosomal proteins	PFC0535w, PF11_0043, PF11_0106, PF13_0171, PF13_0213, PF14_0027
Other	6	Maximal expression during ring/early trophozoite stage, or conflicting stage data	PFE1370w, PF11_0111, PF11_0224, PF14_0277, PF14_0359, PF14_0437

^aThree parasite samples from each of three patients were compared with 11 in vitro microarray time points with highest correlation to each patient [4].
^bLife cycle stages of maximal expression were assigned based on microarray and RNAseq data available from PlasmoDB.org.
RPKM: reads per kilobase per million mapped reads.

ISSN: 1756-994X