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Table 1 Clinical and demographic information for the analysis population

From: An integrated transcriptome and expressed variant analysis of sepsis survival and death

Clinical variable SIRS Sepsis survivors Sepsis non-survivors
n 23 78 28
Age (years) 64.9 ± 14.4 56.1 ± 18.0 67.6 ± 17.0
Gender (% Male) 34.8% 59.0% 60.7%
Race (B/W/O) 16/6/1 47/26/5 21/6/1
APACHE II 16.8 ± 7.7 14.7 ± 6.6 21.3 ± 7.1
Pathogena    
S. aureus N/A 20 (26%) 5 (18%)
S. pneumoniae N/A 20 (26%) 4 (14%)
Enterobacteriaceae N/A 23 (29%) 3 (11%)
Total leukocyte countb 11.2 (8.8, 13.5) 14.6 (9.7, 18.7) 15.1 (10.4, 21.9)
% Neutrophils 77.0 (73.5, 83.3) 85.0 (82.0, 91.0) 87.4 (82.0, 92.8)
% Lymphocytes 13.0 (7.6, 15.8) 7.0 (4.0, 11.0) 8.0 (4.2, 11.8)
% Monocytes 7.1 (4.4, 9.8) 5.0 (3.0, 8.0) 4.5 (2.0, 6.0)
Co-morbidities    
Alcohol abuse 17.4% 17.9% 10.7%
Neoplastic disease 13.0% 6.4% 21.4%
Diabetes 30.4% 32.1% 35.7%
Congestive heart failure 0% 6.4% 14.3%
Chronic kidney disease 26.1% 21.8% 25.0%
Chronic liver disease 8.7% 5.1% 21.4%
Immunosuppression 0% 6.4% 7.1%
Smoker 21.7% 30.8% 25.0%
  1. Data presented as mean ± standard deviation. aOther identified pathogens include: Candida albicans, Clostridium difficile, Coagulase-negative Staphylococcus, Enterococcus species, Legionella, Listeria monocytogenes, Mycoplasma pneumoniae, Pseudomonas aeruginosa, Streptococcus non-pneumoniae (agalactiae, pyogenes, viridans group). No significant differences in pathogen frequency were identified between Sepsis Survivors and Sepsis Non-survivors using Fisher’s exact test. Subjects were counted more than once in cases of polymicrobial infection.
  2. bReported as cells x 109/liter, median (1st quartile, 3rd quartile). Leukocyte differential percentages exclude one SIRS subject, nine Sepsis Survivors, and two Sepsis Deaths for whom differential data were not available.
  3. B/W/O: black/white/other; N/A: not applicable.