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Figure 1 | Genome Medicine

Figure 1

From: Clinical detection and characterization of bacterial pathogens in the genomics era

Figure 1

Applications of bacterial genomics to the management of infectious diseases. Genome sequence analysis has enabled the development of various clinical-microbiology tools for pathogen detection, identification or genotyping by identification of sequence fragments specific at distinct taxonomic levels (genus, species, strain, clone), for the detection of genes associated with antibiotic resistance or virulence and for the identification of deficient metabolisms to aid the development of optimized culture media. However, whole-genome sequencing, by giving access to the full genetic repertoire of an isolate, has demonstrated an undisputed discriminatory power for deciphering outbreaks of infectious diseases.

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