Figure 7
From: Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics
Overlap of changing CpG sites between PDXs originating from the same patient tumour. T1X2A and T1X2B were grown from T1P in two flanks of the same mouse. T1X1 was grown from T1P in a different animal. Overlap percentages were calculated based on the number of changing sites in T1X2B, the PDX with the fewest changes. Over 86% of probes changing in T1X2B also underwent major changes in T1X2A, and over 64% of changes were common between all three PDXs originating from T1P.