Figure 4From: Comparison of DNA methylation profiles in human fetal and adult red blood cell progenitors Erythroid enhancers are enriched for SNPs associated with fetal hemoglobin (HbF) levels in patients with sickle cell disease. Quantile-quantile (QQ) plot of association P values with HbF levels in 1,140 sickle cell disease patients. The QQ plot for all 6,994,357 imputed SNPs is shown in black (λGC = 1.01). In red are the 63,876 markers that map to erythroid enhancers (λGC = 1.03) and in blue are the markers that remain after excluding enhancers near BCL11A, HBS1L-MYB and the β-globin locus (λGC = 1.02).Back to article page