VERSE: a novel approach to detect virus integration in host genomes through reference genome customization

Table 1 Human tumor samples that harbor validated virus integration sites

Tumor type	Virus	Number of samples	Sequencing technology	Number of integration sites	Accession number	Reference
Hepatocellular carcinoma	HBV	13	WGS	20^a	ERP001196	[7]
Hepatocellular carcinoma	HBV	4	RNA-seq	11	SRP023539	[11]
Merkel cell carcinoma	MCV	2	TS	3	NA	[31]

^aTwo virus insertion loci were considered as one if the genomic distance between them was less than 10 bp. HBV, hepatitis B virus; MCV, Merkel cell polyomavirus; NA, no accession number is associated with the project; RNA-seq, whole transcriptome sequencing; TS, targeted sequencing; WGS, whole genome sequencing.

ISSN: 1756-994X