Figure 3From: Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumour Hypermethylated KR-DMRs are enriched in developmental loci and genes involved in β-catenin localisation. Hypermethylated KR-DMRs showed 10.8% enrichment (empirical P ≤ 0.01) for location within domains that are bivalent in embryonic stem cells (considered as developmental loci) compared with levels ascertained by repeated multiple sampling of all array CpGs.Back to article page