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Table 1 Tumour suppressor genes hypermethylated in group-1 Wilms tumours

From: Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumour

Gene

DMR P -value

Hypermethylated WT

Average reads in NR

Average reads in WT

CASP8

0.0037

10 of 13

104

20

H19

0.0045

11 of 13

NA

NA

MIR195

0.0049

13 of 13

NA

NA

RB1

0.0020

13 of 13

55

11

TSPAN32

0.0091

10 of 13

18

8