Lineage trees inferred from 1,088 SNVs from the six patients. Numbers in circles are the number of SNVs that arose in the branch leading to an ancestral node (blue) or that are private to the sample (green). Con, contralateral; Ips, ipsilateral. Stars denote samples originating from at least two lineages. For these samples, the estimated proportions of each lineage’s contribution is denoted by the sizes of the samples’ rectangles. Samples whose branches are drawn rightward at the top of the tree do not harbor any of the assayed SNVs.