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Table 3 Baseline demographic and clinical characteristics of HF and non-HF patients from validation group

From: Gene expression profiling reveals potential prognostic biomarkers associated with the progression of heart failure

Characteristics

HF patients (n = 7)

Non-HF patients (n = 7)

P value

Men

7 (100%)

7 (100%)

NA

Women

0 (0%)

0 (0%)

NA

Age (years)

59.7 ± 9.4

56.7 ± 13.2

0.634

BMI (kg/m2)

30 ± 3.7

26.1 ± 4.2

0.092

Hypertension

5 (71.4%)

5 (71.4%)

1

Diabetes

2 (28.6%)

0 (0%)

0.462

Previous MI

0 (0%)

0 (0%)

NA

Smoking

3 (42.9%)

5 (71.4%)

0.592

Hypercholesterolemia

5 (71.4%)

5 (71.4%)

1

AMI

3 (42.9%)

2 (28.6%)

1

NT-proBNP (pg/mL)a

1,960.9 ± 3,421.9

119.4 ± 118.9

0.002

LVEF (%)a

28.9 ± 6.3

57.7 ± 4.7

<0.001

Medications

Aspirin

7 (100%)

7 (100%)

NA

Clopidogrel

7 (100%)

7 (100%)

NA

Beta blockers

7 (100%)

6 (85.7%)

1

ACE inhibitors

7 (100%)

7 (100%)

NA

Statins

7 (100%)

7 (100%)

NA

Diuretics

5 (71.4%)

1 (14.3%)

0.103

  1. aNT-proBNP, LVEF measured 6 months after AMI.
  2. Data are presented as mean value ± standard deviation or number or percentage of patients. P value <0.05 was considered significant.
  3. ACE, angiotensin-converting enzyme; AMI, anterior myocardial infarction; BMI, body mass index; LVEF, left ventricular ejection fraction; MI, myocardial infarction; NA, not applicable; NT-proBNP, N-terminal pro-brain natriuretic peptide.