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Table 6 RT-qPCR results for selected genes in HF, non-HF, and control groups on admission

From: Gene expression profiling reveals potential prognostic biomarkers associated with the progression of heart failure

Gene symbol

HF vs. non-HF

HF vs. control group

Non-HF vs. control group

 

Microarray

RT-qPCR

RT-qPCR

Microarray

RT-qPCR

RT-qPCR

Microarray

RT-qPCR

RT-qPCR

Study group

Study group

Validation group

Study group

Study group

Validation group

Study group

Study group

Validation group

 

Fold change

P value

Fold change

P value

Fold change

P value

Fold change

P value

Fold change

P value

Fold change

P value

Fold change

P value

Fold change

P value

Fold change

P value

FMN1

2.765

***

2.173

*

1.843

*

3.081

***

2.659

*

3.207

*

1.114

ns

1.223

ns

1.641

ns

JDP2

1.825

***

1.823

**

1.506

*

1.597

**

2.548

***

2.893

***

-1.142

ns

1.398

**

1.933

**

RNASE1

2.044

**

3.791

**

3.007

*

2.612

***

5.014

***

6.362

***

1.278

ns

1.323

ns

2.677

*

TIMP1

1.523

**

1.498

**

1.681

**

1.421

**

-1.055

ns

2.250

**

-1.072

ns

-1.580

**

1.346

ns

  1. Statistical significance: *P <0.05. **P <0.01. ***P <0.001.
  2. Results were normalized to HPRT1.
  3. ns, non-significant.