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Figure 3 | Genome Medicine

Figure 3

From: Molecular insight into thiopurine resistance: transcriptomic signature in lymphoblastoid cell lines

Figure 3

Top Ingenuity® canonical pathways enriched by genes that were significantly differentially expressed in resistant cell lines. The Ingenuity® canonical pathway analysis associates the 943 gene dataset with the canonical pathways in Ingenuity’s Knowledge Base and returns two measures of association: (1) a ratio of the number of genes from the list that maps to the pathway divided by the total number of genes that map to the same pathway, and (2) a P value of the Fisher’s exact test for each pathway. Ingenuity® canonical pathways associated with a P value <0.01 are presented.

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