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Table 1 Characteristics of lymphoblastoid cell lines

From: Molecular insight into thiopurine resistance: transcriptomic signature in lymphoblastoid cell lines

  Resistant (n = 5) Sensitive (n = 6) P
Growth inhibition by 6-MP (%) 11.8 ± 2.1 39.8 ± 2.3 0.008
Basal growth rate per day 0.3 ± 0.06 0.5 ± 0.04 0.052
EBV copy number (absolute) 110 ± 35 47 ± 11 0.17
mtDNA copy number (relative) 1.5 ± 0.2 2.4 ± 0.3 0.08
Intracellular ATP level (μmol/106 cells) 23.9 ± 2.6 19.0 ± 1.8 0.25
TPMT activity (pmol/h/mg protein) 425 ± 20 295 ± 24 0.024
HPRT activity (nmol/h/mg protein) 621 ± 12 576 ± 57 1.0