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Table 2 Gene ontology terms involved in the phenotypic difference between resistant and sensitive cell lines

From: Molecular insight into thiopurine resistance: transcriptomic signature in lymphoblastoid cell lines

GO ref

GO term

Genes (n)

Fold enrichment

P value

Benjamini corrected P value

 

GO:0022613

Ribonucleoprotein complex biogenesis

27

3.53

4.17E-08

9.26E-05

RNA processes

GO:0006396

RNA processing

52

2.24

9.74E-08

1.08E-04

GO:0034660

ncRNA metabolic process

29

2.97

4.99E-07

3.69E-04

GO:0042254

Ribosome biogenesis

20

3.86

8.66E-07

4.81E-04

GO:0034470

ncRNA processing

23

2.89

1.44E-05

3.99E-03

GO:0022402

Cell cycle process

49

2.04

3.45E-06

1.53E-03

Cell cycle

GO:0007049

Cell cycle

60

1.82

8.61E-06

3.18E-03

GO:0000279

M phase

33

2.36

1.08E-05

3.41E-03

GO:0022403

Cell cycle phase

38

2.16

1.54E-05

3.79E-03

GO:0000278

Mitotic cell cycle

35

2.23

1.91E-05

4.24E-03

  1. Significance level Benjamini corrected P value <0.01.
  2. List of genes represented by these terms is presented in Additional file 1: Table S6.