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Table 1 Eligibility criteria for BRIDGE bleeding and platelet disorders study

From: Human phenotype ontology annotation and cluster analysis to unravel genetic defects in 707 cases with unexplained bleeding and platelet disorders

Inclusion criteria Exclusion criteria
Platelet count less than 100 × 109/L or greater than 400 × 109/L, or Acquired bleeding or platelet disorders, including any of the following:
Mean platelet volume less than 6 fL or greater than 12 fL, or Use of any medication known to affect platelet function or cause bleeding
Reproducible abnormal platelet function test results, or Immune thrombocytopenia
Abnormal platelet morphology by light or electron microscopy, or HIV infection
Pathological bleeding of unknown aetiology, and Malignancies, particularly those affecting haemopoiesis
Considered by referring clinician to be of genetic aetiology Bone marrow aplasia
  Thrombotic thrombocytopenic purpura/ Haemolytic-uremic syndrome
  Acute viral infection
  Uraemia or hepatic failure