Figure 3

Overlap of differentially expressed lncRNAs and protein-coding genes between iCD and iUC. (A,B) Venn diagrams show an overlap of 337 lncRNAs (A) and 901 protein-coding genes (B) that were differentially expressed (FC >1.5, adjusted P-value <0.05) between patients with iCD and iUC compared with healthy controls. We observed contra-regulated genes between iCD/iUC versus control comparisons compared with the iCD versus iUC comparison. The up-regulated genes are depicted in italics, down-regulated as underlined and contra-regulated in red. (C,D) Heat maps of average normalized gene expression for the overlapping 337 lncRNAs (C) and 901 protein-coding genes (D) between iCD and iUC in the five clinical subgroups (iCD, niCD, iUC, niUC and controls) are displayed. Selected up-regulated and down-regulated genes are listed.