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Table 5 Top 10 differentially expressed lncRNA and protein-coding genes in inflamed ulcerative colitis

From: Transcriptomic landscape of lncRNAs in inflammatory bowel disease

Gene name Transcript FC
Up-regulated lncRNAs   
  RP11-731 F5.2 ENST00000460164.1 20.64
  MMP12 ENST00000532855.1 17.05
  MMP12 ENST00000326227.5 16.54
  RP11-465 L10.10 ENST00000419897.1 9.52
  KIF9-AS1 ENST00000429315.2 5.75
  FAM66D ENST00000526690.1 5.73
  SAA2-SAA4 ENST00000524555.1 5.66
  CLRN1-AS1 ENST00000476886.1 4.64
  RP11-1149O23.3 ENST00000517774.1 4.29
  RP5-1028 K7.2 ENST00000578280.1 4.21
Down-regulated lncRNAs   
  ANRIL (CDKN2B-AS1) ENST00000422420.1 -8.67
  ANRIL (CDKN2B-AS1) ENST00000428597.1 -8.31
  ANRIL (CDKN2B-AS1) ENST00000585267.1 -7.06
  ANRIL (CDKN2B-AS1) ENST00000580576.1 -6.92
  ANRIL (CDKN2B-AS1) ENST00000577551.1 -6.74
  ANRIL (CDKN2B-AS1) ENST00000581051.1 -6.72
  ANRIL (CDKN2B-AS1) ENST00000582072.1 -6.68
  PDZK1P2 ENST00000401008.2 -6.67
  DPP10-AS1 ENST00000432658.1 -5.95
  ANRIL (CDKN2B-AS1) ENST00000421632.1 -5.78
Up-regulated protein-coding genes   
  DUOXA2 NM_207581 109.61
  CHI3L1 NM_001276 39.71
  SAA1 NM_000331 30.67
  CXCL1 NM_001511 25.92
  MMP7 NM_002423 21.2
  SLC6A14 NM_007231 20.52
  IGHG3 ENST00000390551 20.14
  MMP12 NM_002426 15.76
  C4orf7 NM_152997 14.76
  CXCL2 NM_002089 11.91
Down-regulated protein-coding genes   
  PCK1 NM_002591 -15.24
  OSTalpha NM_152672 -11.33
  ANPEP NM_001150 -11.02
  SLC26A2 NM_000112 -10.46
  GBA3 NM_020973 -9.28
  GUCA2A NM_033553 -9.22
  SLC3A1 NM_000341 -9.21
  GUCA2B NM_007102 -8.84
  TMIGD1 NM_206832 -8.17
  SLC1A7 NM_006671 -6.57
  1. Top 10 up- and down-regulated lncRNA and protein-coding genes in iUC versus control comparison. The log2 fold change is denoted as FC.