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Fig. 3 | Genome Medicine

Fig. 3

From: Virulence genes are a signature of the microbiome in the colorectal tumor microenvironment

Fig. 3

Relationships among the taxa found in colorectal cancer patients’ microbiomes. a Phylogenetic tree depicting the relatedness of the bacterial taxa present (>0.1 % of total) within 50 % or more of the samples. The bars to the right indicate the –log10(p value) from the Wilcoxon signed rank test to determine differential abundance between the normal and tumor microbiomes. Red bars indicate significance at 10 % FDR, while gray bars indicate that the specific taxon did not reach significance. b Correlation network showing the relationship among the abundances of genera with absolute values of 0.05 or more and statistical significance (pseudo p value <0.05). Edges indicate correlations: the edge thickness represents the magnitude and the color represents the sign (blue is positive correlation, red is negative correlation). Each node is a microbial genus where diamond shaped nodes indicate a higher average abundance and circular nodes indicate a lower average abundance in the tumor microbiome compared with normal

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