Table 1 Summary statistics of demographic data for the eMERGE participants with PGRNSeq data by self-reported sex and race
Female | Male | Combined | |
|---|---|---|---|
(N=546) | (N=348) | (N=894) | |
Self-Reported Race | |||
American Indian orAlaska Native | 2 %(9) | 1 %(2) | 1 %(11) |
Asian | 9 %(50) | 5 %(19) | 8 %(69) |
Black or African American | 5 %(29) | 3 %(12) | 5 %(41) |
Native Hawaiian or otherPacific Islander | 0 %(2) | 0 %(0) | 0 %(2) |
Unknown | 1 %(4) | 5 %(16) | 2 %(20) |
White | 83 %(452) | 86 %(299) | 84 %(751) |
Ethnicity | |||
No | 95 %(520) | 94 %(326) | 95 %(846) |
Yes | 4 %(24) | 2 %(6) | 3 %(30) |
Unknown | 0 %(2) | 5 %(16) | 2 %(18) |
Hx a of LQTS | 0 %(0) | 1 %(2) | 0 %(2) |
Hx of Hypertension | 79 %(429) | 80 %(279) | 79 %(708) |
Hx of Arrhythmia | 48 %(264) | 53 %(186) | 50 %(450) |
Hx of AF | 7 %(38) | 14 %(47) | 10 %(85) |
Hx of CHF | 1 %(6) | 3 %(12) | 2 %(18) |
Median LDL \(> 155\frac {mg}{dL}\) | 9 %(50) | 6 %(22) | 8 %(72) |
Median Triglyceride\(> 22\frac {mg}{dL}\) | 6 %(33) | 11 %(40) | 8 %(73) |
Median CK \( > 174\frac {IU}{L}\) | 1 %(4) | 7 %(23) | 3 %(27) |
Median TSH \(> 4\frac {\mu g}{dL}\) | 6 %(34) | 4 %(13) | 5 %(47) |
Median INR >1.5 | 7 %(36) | 11 %(40) | 9 %(76) |
Total PGx Variants(total variants) | 75.8±15.9 | 74.3±12.8 | 75.2±14.7 |
Coding PGx Variants(coding variants) | 11.6±4.2 | 11.4±3.5 | 11.5±3.9 |
Group Health PGx Variants (gh variants) | 40.0±9.6 | 38.5±8.7 | 39.4±9.3 |