Fig. 2
From: Inferring pathway dysregulation in cancers from multiple types of omic data
Results of cross-algorithm comparisons on simulated data. We compared GSOA against other methods using simulated data that contained interdependence among variables. For various FDR thresholds, we calculated the proportion of simulated gene sets containing signal that were considered significant and the proportion of gene sets containing only random data that were considered insignificant. Panels a-c show results for balanced data (50/50 sample split); Panels d-f show results for unbalanced data (90/10 sample split). See also Additional file 1: Fig. S4