Table 2 Validation and comparison to other methods in a p53 benchmark microarray dataset

P53 pathway

1

0.001

0.037

1

0.000

0.009

26

0.093

0.822

1

0.000

0.566

P53 signaling

15

0.002

0.058

21

0.028

0.614

30

0.109

0.822

29

0.048

0.695

P53 hypoxia pathway

1

0.001

0.037

1

0.000

0.009

27

0.103

0.822

5

0.002

0.713

P53 up

1

0.001

0.037

1

0.000

0.065

20

0.083

0.822

1

0.000

0.595

DNA damage signaling

1

0.001

0.037

80

0.223

1

5

0.043

0.822

40

0.061

0.693

Radiation sensitivity

1

0.001

0.037

6

0.002

0.088

18

0.077

0.822

11

0.014

0.621

Cell cycle regulator

1

0.001

0.037

116

0.330

1

4

0.042

0.822

20

0.030

0.571

Cell cycle pathway

1

0.001

0.037

237

0.729

0.949

17

0.075

0.822

55

0.104

0.593

Cell cycle

15

0.002

0.058

172

0.531

0.930

7

0.046

0.822

93

0.175

1

Cell cycle arrest

43

0.021

0.255

166

0.509

0.887

41

0.141

0.822

216

0.396

1

Ras pathway

39

0.016

0.209

7

0.002

0.284

64

0.186

0.822

312

0.565

1

MAPK cascade

50

0.040

0.418

16

0.021

0.494

57

0.177

0.822

107

0.204

1

# of sig. gene sets