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Fig. 2 | Genome Medicine

Fig. 2

From: Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors

Fig. 2

Candidate driver genes in MOTs. Significantly mutated genes identified by OncodriveFM and MuSiC analyses are arranged vertically by their frequency of mutated samples in the whole exome sequencing data. Color indicates mutation consequence. Selected genes were also investigated in a validation cohort of mucinous tumors. Each column denotes an individual tumor (ordered as listed in Additional file 1: Table S1), which have been arranged to emphasize mutational groups. Genomic aberrations in other MAPK pathway genes were also screened for mutations. LOH loss of heterozygosity

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