Fig. 5

CNV burden in autism and ID/DD cohorts. Population frequency of the largest CNV in individuals with autism, ID/DD, epilepsy, and/or other comorbidities is shown. Using the rare CNV cohort, survivor functions were generated for the population frequency carrying a CNV larger than a given size. CNV burden plots are shown for: (a) boys (dashed lines) and girls (solid lines) with autism with or without any comorbidities; (b) boys (dashed lines) and girls (solid lines) with ID/DD with or without any comorbidities; (c) boys (dashed lines) and girls (solid lines) with autism with ID, autism with epilepsy, and ID with epilepsy are shown. Full statistical analysis including sample sizes (n) is provided in Additional file 1: Table S11