Fig. 5

a Co-mutation map showing alterations in genes involved in chromatin remodeling in 25 (42 %) oral tongue squamous cell carcinoma (OTSCC) samples. Gene names and mutation rates are as indicated on either side of the plot, while the type of mutation follows the legend below. b Comparison between OTSCC, the oral cavity cohort from TCGA (OC-TCGA) and the entire head and neck cohort of TCGA (HN-TCGA) for frequency of genetic alterations in ten chromatin remodeling genes. P value based on t-test; NS not significant. c Kaplan-Meier plot showing DFS estimates according to the mutational status of the chromatin remodeling family. P value is based on log-rank test. d, e Results of multivariate analysis of selected prognostic factors for DFS in OTSCC by Cox proportional hazards model. HR hazard ratio