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Table 1 Description of the discovery samples

From: Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers

  Sub-group 1 Sub-group 2 Total
n 130 225 355
nmales 37 (29 %) 177 (79 %) 214 (60 %)
Age (years)a 15.3 ± 0.64 23.6 ± 3.3 20.6 ± 1.2
Weight (kg)a 72.9 ± 11.4 76.6 ± 12.4 71.6 ± 13.7
Height (m)a 1.70 ± 0.081 1.79 ± 0.078 1.76 ± 0.092
Weight categoryb 77 % lean, 18 % overweight, 5 % obese 74 % lean, 21 % overweight, 5 % obese 76 % lean, 20 % overweight, 4 % obese
  1. aMean ± standard deviation. bFor individuals aged under 18 years, we used Cole et al.’s definition to determine weight category [39]. For individuals aged 18 years and older, the following cutoffs were used: lean, BMI < 25; overweight, 25 ≤ BMI < 30; obese, BMI ≥ 30