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Table 1 Description of the discovery samples

From: Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers

 

Sub-group 1

Sub-group 2

Total

n

130

225

355

nmales

37 (29 %)

177 (79 %)

214 (60 %)

Age (years)a

15.3 ± 0.64

23.6 ± 3.3

20.6 ± 1.2

Weight (kg)a

72.9 ± 11.4

76.6 ± 12.4

71.6 ± 13.7

Height (m)a

1.70 ± 0.081

1.79 ± 0.078

1.76 ± 0.092

Weight categoryb

77 % lean, 18 % overweight, 5 % obese

74 % lean, 21 % overweight, 5 % obese

76 % lean, 20 % overweight, 4 % obese

  1. aMean ± standard deviation. bFor individuals aged under 18 years, we used Cole et al.’s definition to determine weight category [39]. For individuals aged 18 years and older, the following cutoffs were used: lean, BMI < 25; overweight, 25 ≤ BMI < 30; obese, BMI ≥ 30