A genome-wide approach to link genotype to clinical outcome by utilizing next generation sequencing and gene chip data of 6,697 breast cancer patients

Table 1 A list of the top 20 most common cancer and non-cancer (based on Cosmic) mutations identified by analyzing 763 breast cancer samples

^aVersion: COSMICv71
A significance threshold of 0.01 and a minimal AUC of 0.65 are required for each gene to be considered as significant in the ROC analysis, and the threshold for significance in the survival analysis was set at P <0.05 and average HR >1.4. This analysis included all genes (including the established driver genes as well)

ISSN: 1756-994X