Table 2 GeneNetwork results over all cis-eQTLs
| Â | Pathway or process | P-value |
|---|---|---|
GO: BP | co-factor biosynthetic process | 1 × 10−18 |
|  | co-factor metabolic process | 6 × 10−18 |
|  | water-soluble vitamin metabolic process | 3 × 10−17 |
GO: CC | mitochondrial matrix | 5 × 10−13 |
|  | organelle outer membrane | 1 × 10−12 |
|  | outer membrane | 2 × 10−12 |
GO: MF | transferase activity, transferring alkyl or aryl (other than methyl) groups | 2 × 10−17 |
|  | co-enzyme binding | 3 × 10−14 |
|  | co-factor binding | 3 × 10−13 |
KEGG | amino sugar and nucleotide sugar metabolism | 1 × 10−12 |
|  | pyrimidine metabolism | 4 × 10−10 |
|  | glutathione metabolism | 4 × 10−9 |
Reactome | metabolism of water-soluble vitamins and co-factors | 3 × 10−16 |
|  | metabolism of vitamins and co-factors | 3 × 10−16 |
|  | mitochondrial tRNA amino-acylation | 6 × 10−16 |
MGI | abnormal inhibitory postsynaptic currents | 3 × 10−11 |
|  | abnormal cell morphology | 7 × 10−11 |
|  | abnormal circulating amino acid level | 9 × 10−10 |
Tissues and cells | adipocytes | 1 × 10−48 |
choroid | 3 × 10−48 | |
aortic valve | 8 × 10−47 | |
subcutaneous fat | 10 × 10−46 | |
subcutaneous fat, abdominal | 2 × 10−45 |