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Fig. 3 | Genome Medicine

Fig. 3

From: Clinical metagenomic identification of Balamuthia mandrillaris encephalitis and assembly of the draft genome: the continuing case for reference genome sequencing

Fig. 3

Phylogenetic trees of the mitochondrial cox1 protein and 28S rRNA gene reveal the close phylogenetic relationship between Balamuthia and Acanthamoeba. a Phylogeny of seven Balamuthia cox1 amino acid sequences along with the top complete sequence hits in NCBI nr ranked by BLASTp E-score. b Phylogeny of seven Balamuthia 23S rRNA nucleotide sequences along with the top complete sequence hits in NCBI nt ranked by BLASTn E-score. Sequences were aligned using MUSCLE and a phylogenetic tree constructed using MrBayes. Branch lengths are drawn proportionally to the number of nucleotide substitutions per position, and support values are shown for each node

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