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Fig. 4 | Genome Medicine

Fig. 4

From: Annotation of pseudogenic gene segments by massively parallel sequencing of rearranged lymphocyte receptor loci

Fig. 4

Heat map showing the percent productive rearrangements for all TCRβ V gene segments throughout the cohort. The percentage of productive TCRβ V rearrangements found in mature T cells is shown for each of the 587 individuals in the cohort for each V gene segment included in this study (listed to the left of the heat map). The column labeled “Key” indicates the color code: gene segments found in a high percentage of productive rearrangements in that individual are indicated in red, while gene segments with low frequencies of productive rearrangement in that individual are shown in blue. The next two columns indicate the mean percentage of each V gene segment found in productive rearrangements across all individuals; values over 56.7 % are displayed in green while values under 56.7 % are shown in purple. The next column corresponds to the standard deviation, with values under and over 5 % shown in green and purple, respectively. V gene segments are classified by their current IMGT annotation as shown in the column labeled IMTG (F functional, P pseudogene, ORF open reading frame, F/P or F/ORF genes with multiple alleles that differ in their functional annotation), and sorted by percent productive rearrangement within each category. The last column indicates the functionality of the alleles observed in this study. Discrepancies annotations between this study and IMGT are bolded

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